Browsing by Title
Now showing items 532-551 of 2497
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Department chairs' perceptions of music transfer student success.
(2007-02-14)The purpose of this study was to describe and understand the perceptions department chairs had of various attributes that contributed to two-year music transfer student success, in upper-level instruction at a four-year ... -
Depositional and diagenetic controls on reservoir quality and their petrophysical predictors within the Upper Cretaceous (Cenomanian) Doe Creek Member of the Kaskapau Formation at Valhalla Field, Northwest Alberta.
(2009-04-03)Valhalla Field, discovered in 1979 and located in northwest Alberta, produces from the Upper Cretaceous Doe Creek Member of the Kaskapau Formation. Original reserves in place are 44 x 106m3 of oil, of which 10.3 x 106m3 ... -
Depositional character of Late Triassic fluvial and lacustrine strata of the Owl Rock Member (Chinle Formation), Petrified Forest National Park, Arizona.
(2014-11-07)This study provides stratigraphic motifs and depositional reconstructions for the Late Triassic (Norian-Rhaetian) Owl Rock Member of the Chinle Formation located at Chinde Mesa, Petrified Forest National Park (PFNP), AZ. ... -
A Descriptive Study of Protective Tissue Formation in Stems of Quercus buckleyi Nixon & Dorr (Fagaceae)
(2012-04-25)The epidermis and periderm are two components of the protective tissues that cover plant stems and roots. The epidermis is the first protective layer of the plant, and is later replaced by the periderm, which is typically ... -
Design and experimental testing of small-scale wind turbines.
(2011-05-12)Due to the increasing environmental and economic cost of fossil fuels, alternative sources of energy are needed. One such source is energy wind energy. Much of the current wind turbine research focuses on large-scale wind ... -
Design and implementation of a multi-agent optimized control system for a large-scale fossil-fuel electrical power unit.
(, 2011-12-19)The problem facing the United Sates electric power industry today can be attributed to society’s ever increasing demand for energy, environmental concerns with reliance on fossil fuels, and uncertainty about an aging ... -
Design and implementation of a synthetic aperture radar (SAR) imaging system using an ultra-wideband (UWB) radar sensor.
(2016-04-14)This thesis documents the design and implementation of a radar imaging system. A rail system was constructed to control the location of an off-the-shelf ultra-wideband (UWB) radar along a linear path. Range imaging, ... -
Design and modeling of a power conditioning system for the hybrid fuel-cell/turbine power plant.
(, 2011-09-14)This thesis presents the model of a power conditioning system (PCS) for the hybrid direct fuel-cell with turbine (DFC/T) power plant. It regulates voltage, current and power transmitted from the hybrid DFC/T power plant ... -
Design and synthesis of combretastatin A-1 analogs, small molecule vascular disrupting agents, and bioreductive triggers as potential therapeutic agents for the treatment of cancer.
(2011-01-05)Cancer is the second leading cause of death in the United States with over 550,000 deaths in 2009 and a devastating 7.9 million deaths worldwide in 2007. Vascular disrupting agents (VDAs) represent a novel method developed ... -
Design and synthesis of dihydronaphthalene vascular disrupting agents and indolequinone-based bioreductives.
(2007-03-08)Cancer remains a deadly affliction for millions across the United States, and the number of new cases is only expected to rise in the years to come. In the field of anticancer research, vascular disrupting agents (VDAs) ... -
Design and synthesis of functionalized small-molecule inhibitors of cathepsins L and K.
(, 2012-08-08)Inhibition of a class of cysteine proteases known as the cathepsins has received increasing attention in recent years, since these enzymes play key roles in cancer metastasis. Cathepsins B, K, and L have been of particular ... -
Design and Synthesis of Functionalized Thiosemicarbazone Analogues as Potential Anti-metastatic Agents
(2013-05-24)Metastasis is often the ultimate cause of death among cancer patients. An emerging target in the treatment of metastasis is cathepsin L which facilitates the degradation of the extracellular matrix thereby providing a ... -
Design and synthesis of non-peptidic thiosemicarbazone derivatives as inhibitors of cathepsins L and K.
(2012-11-29)Cathepsin L, a member of the lysosome cysteine proteases, is ubiquitously expressed in tissue and is responsible for protein turnover. An overexpression of cathepsin L by certain tumor types is associated with enhanced ... -
Design and Synthesis of Novel Vascular Disrupting Agents With Potential Chemotherapeutic Properties
(2013-05-23)The term cancer is a widely universal label for a cluster of cells that can divide uncontrollably and invade the surrounding healthy tissue. Vascular targeting agents (VTAs) represent an important and emerging area of ... -
Design and synthesis of novel β-cyclodextrins and their application as chiral stationary phases for gas chromatography.
(2011-01-05)Enantiomers can be directly separated only with use of systems containing a chiral selector. Cyclodextrins (CDs) and modified cyclodextrins have been used as chiral selectors for their ability to form host-guest complexes ... -
Design and synthesis of potential serotonin-selective reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors for the treatment of depression.
(2010-10-08)Depression is a common disease characterized by feelings of deep sadness, guiltiness, loss of interest in once pleasurable activities, and thoughts of self-harm among others. Affecting an estimated 121 million people ... -
The Design and Synthesis of Small-Molecule Anticancer Agents Targeted Through Antibody-Drug Conjugates
(2014-05-01)A relatively recent addition to the arsenal of potential treatments for cancer involves the use of vascular disrupting agents (VDAs). Small-molecule VDAs target the blood supply of a tumor, starving it of nutrients and ... -
Design and synthesis of small-molecule inhibitors of cathepsin L bearing the thiosemicarbazone warhead as potential anti-metastatic agents.
(2015-11-18)Mestastasis is a devastating component associated with tumor progression which claims the majority of lives lost to cancer. Upregulation of cathepsin L, a powerful cysteine protease capable of degrading components in the ... -
Design and Synthesis of Vascular Disrupting Agents that Bear the Indole Molecular Framework
(2016-08-09)The discovery of colchicine and combretastatin A-4 (CA4), two naturally occurring compounds that inhibit tubulin polymerization, have spurred great interest in small-molecule anticancer agents that interact with the ... -
Design and validation of a solar domestic hot water heating simulator.
(2009-07-08)A growing demand for emerging alternative energy technologies is fueled by rising energy prices and decreasing energy supplies. Domestic hot water heating is an industry that continues to benefit from increased research ...