Now showing items 21-40 of 837

• Structure-activity relationships and thermodynamics of combretastatin A-4 and A-1 derivatives as potential inhibitors of tubulin polymerization. ﻿

(2006-05-29)
Inhibition of tubulin polymerization has been identified as a significant characteristic of potential anticancer agents. Tubulin is a heterodimeric protein of a and b polypepetide chains, each with a molecular weight of ...
• Discovery and development of unique small molecule chromene based ligands and combretastatin analogs as potential second generation vascular disrupting agents towards cancer chemotherapy. ﻿

(2006-05-29)
Cancer is a devastating disease, which remains one of the leading causes of death worldwide. In our continuing quest to help find a cure for cancer, we have discovered and developed new small molecule vascular disrupting ...
• Effects of chiral contaminants to aquatic organisms: pharmaceuticals as model compounds for enantiomer specific ecological hazard assessment. ﻿

(Houston, Texas : SETAC Press., 2006-07)
In the present study, enantiospecific effects of chiral contaminants were explored using two chiral pharmaceutical contaminants as model compounds. These compounds are the selective serotonin reuptake inhibitor antidepressant ...
• Uniqueness implies uniqueness and existence for nonlocal boundary value problems for fourth order differential equations. ﻿

(2006-07-07)
In this dissertation, we are concerned with uniqueness and existence of solutions of certain types of boundary value problems for fourth order differential equations. In particular, we deal with uniqueness implies uniqueness ...
• The narrative effect of Book IV of the Hebrew Psalter. ﻿

(2006-07-21)
This dissertation asserts that a reader encountering the canonical Hebrew Psalter can read from the beginning and capture a sense of plot. The turning point of the story is Book IV (Psalms 90-106). It is at this point ...
• Race, faith and fear: general press and black press coverage of Arabs, Muslims and the stigma of terrorism in the United States. ﻿

(2006-07-22)
The global impact of the events of September 11, 2001, provoked an interest in American media coverage of terrorism. With African-Americans making up more than 12 percent of the country’s population and more than 40 percent ...
• A case study of two Cherokee newspapers and their fight against censorship. ﻿

(2006-07-22)
This study attempts to illuminate an injustice to the Cherokee Nation through denial of First Amendment rights in newspapers and communities. Through case studies and in-depth interviews it examines the avenues by which ...
• Conjugate hierarchical models for spatial data: an application on an optimal selection procedure. ﻿

(2006-07-24)
The theory of generalized linear models provides a unifying class of statistical distributions that can be used to model both discrete and continuous events. In this dissertation we present a new conjugate hierarchical ...
• Ontology, exegesis, and culture in the thought of Henri de Lubac. ﻿

(2006-07-24)
This dissertation examines the continuity between Henri de Lubac's retrieval of patristic and medieval exegesis and his treatment of the ontological relationship between nature and grace. I argue that, for de Lubac, the ...
• Foreign language learning: an exploratory study on the external and internal influences affecting success. ﻿

(2006-07-24)
This study explores the influence that determinants such as age, length of exposure, learning environment, personality, attitude, study habits, personal practice, and personal motivation have on individuals studying a ...
• Expanding the new paradigm: winners and losers among exclusive and nonexclusive religious firms in the Chinese and Japanese communities in the United States, 1850-1945. ﻿

(2006-07-24)
From the perspective of a refined religious economy theory, the present paper is the first to empirically study the interplay between exclusive and nonexclusive religious bodies. Through reconstructing the historical facts ...
• Gestos posmodernos en la novela latinoamericana: los casos de Cristina Rivera Garza, Ana Maria Shua y Laura Restrepo. ﻿

(2006-07-24)
Proponemos en esta tesis que las novelas La muerte como efecto secundario (1997) de Ana María Shua (1951), La cresta de llión (2003) de Cristina Rivera Garza (1961) y Delirio (2004) de Laura Restrepo (1955) exhiben gestos ...
• The Catholic Church and the nonviolent resistance in Chile. ﻿

(2006-07-25)
When can nonviolent action be effective? That is the question that originally initiated this research project. While studying the different factors scholars believe to be important to a successful nonviolent action, I ...
• A novel spectropolarimeter for determiation of sucrose and other optically active samples. ﻿

(2006-07-25)
Polarimetry and spectropolarimetry are important tools in the sugar industry and pharmaceutical research. Polarimetric measurements cannot be performed on colored samples because the presence of color interferes with the ...
• Subversive pseudo-dialogic: W.B. Yeats's use of the dialogic to present the monologic. ﻿

(2006-07-25)
The application of Mikhail Bakhtin's theory of the dialogic provides unique insight into the poetry and plays of W.B. Yeats. Though this early twentieth century Irish writer favored poetry over the novel form on which ...
• Fidelity to God: perseverance in Hebrews in light of the reciprocity systems of the ancient Mediterranean world. ﻿

(2006-07-25)
The primary focus of this dissertation is to demonstrate how Hebrews represents, in view of its historical and religious context, human fidelity to God. Reciprocity was one primary dynamic in the ancient Mediterranean ...
• Uniqueness implies uniqueness and existence for nonlocal boundary value problems for third order ordinary differential equations. ﻿

(2006-07-29)
For the third order ordinary differential equation, $y'''=f(x,y,y',y'')$, it is assumed that, for some $m\geq 4$, solutions of nonlocal boundary value problems satisfying $y(x_1)=y_1,\ y(x_2)=y_2,$ \[y(x_m)-\sum_{i= ...
• Bayesian evaluation of surrogate endpoints. ﻿

(2006-07-29)
To save time and reduce the size and cost of clinical trials, surrogate endpoints are frequently measured instead of true endpoints. The proportion of the treatment effect explained by surrogate endpoints (PTE) is a widely ...
• Conceiving coexistence: an exposition on the divergent Western and Islamic conceptualizations of tolerance. ﻿

(2006-07-29)
This dissertation provides a brief analysis of select writings and practics of tolerance in Western and Islamic histories to show how an intercultural understanding of tolerance is well within the philosophical, theological, ...
• The fantastic and related subgenres in three contemporary novels. ﻿

(2006-07-29)
Louise Erdrich's Love Medicine (1984), Amy Tan's The Bonesetter's Daughter (2001), and Cynthia Ozick's The Puttermesser Papers (1997) manifest the fantastic and related subgenres. According to structuralist critic Tzvetan ...