Show simple item record

dc.contributor.advisorAbell, Troy
dc.contributor.authorFrensley, Alexandra
dc.date.accessioned2012-05-02T18:34:07Z
dc.date.available2012-05-02T18:34:07Z
dc.date.copyright2012-04-26
dc.date.issued2012-05-02
dc.identifier.urihttp://hdl.handle.net/2104/8351
dc.description.abstractIn order to maximize the number of infants weighing in the birthweight range associated with the lowest amount of morbidity and mortality (2,500-4,000 grams) the complex interactions between the anthropometric, social, and environmental factors that influence birthweight need to be better understood. Currently, maternal gestational weight gain recommendations are based on body mass index (BMI). However, BMI is a measurement of total maternal adiposity and does not account for fat specialization during pregnancy. It is hypothesized that upper body maternal fat stores are used to fuel fetal growth during pregnancy whereas thigh fat stores are reserved for lactation. Therefore, it is expected that maternal pre-pregnancy upper body fat will correlate with infant birthweight and lower body fat stores will not. This NIH-funded prospective cohort study follows 1,206 mother-infant pairs from first prenatal visit to after delivery with the objective of investigating the impact of maternal height, pre-pregnancy fat distribution, and gestational weight gain on infant birthweight. When birthweight was regressed on traditional determinants of birthweight (gestational age, sex of the infant, parity of the mother, maternal ethnicity, and smoking status) and maternal height, maternal gestational weight gain, circumference of the forearm at the beginning of pregnancy, and subscapular skinfold measurement at the beginning of pregnancy, 0.5423 of the variance in infant birthweight was explained (p = 0 .0001). Thigh adiposity was not associated with infant birthweight (p = 0.9819) and did not add to the explained variance. These results indicate that upper body fat directly contributes to fetal growth during pregnancy, with infant birthweight being independent of pre-pregnancy lower body fat stores. This is consistent with the growing body of knowledge that lower body fat stores primarily are used for lactation.en_US
dc.language.isoen_USen_US
dc.rightsBaylor University projects are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. Contact libraryquestions@baylor.edu for inquiries about permission.en_US
dc.subjectFetal Growthen_US
dc.titleThe Effect of Maternal Fat Specialization on Infant Birthweighten_US
dc.typeThesisen_US
dc.rights.accessrightsWorldwide accessen_US
dc.contributor.departmentUniversity Scholars - Honors Programen_US
dc.contributor.schoolshonors collegeen_US


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record