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Now showing items 2743-2762 of 3146
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Tackling difficult dialogues: a director's approach to Rebecca Gilman's "Spinning Into Butter".
(2008-04-15)Tackling difficult dialogues, playwright Rebecca Gilman bravely explores big questions. Gilman is a worthy candidate for literary and performance study because her work documents the most compelling issues facing our ... -
Tailoring Forensic Interviews to Developmental Level of Verbal Ability in Victims of Child Sexual Assault
(2018-05-21)Performing legally sound forensic interviews is an integral part of any court case. However, the same methods used for adults are not effective for children, and in order to obtain a testimony that will be admissible as ... -
Take me to the movie show : curating and creating digital content.
(2014-06-11)The digital presence of museums has continually grown in recent years. This project examines the processes of digitizing a collection and creating digital content. The goals of this project were to select 155 pieces from ... -
Taken for granted? Exploring the relationships between social service agencies and religious congregations.
(2006-07-30)Religious congregations play a significant role in the provision of social services in American communities. While some congregations establish their own social service programs, most do not. Instead, the majority of ... -
Taking responsibility for ourselves : a Kiekergaardian account of the freedom of the freedom-relevant conditions necessary for the cultivation of character.
(2011-05-12)What are the freedom-relevant conditions necessary for someone to be a morally responsible person? I examine several key authors beginning with Harry Frankfurt that have contributed to this debate in recent years, and ... -
Taphonomic and mass-extinction research from an ichnological perspective.
(2018-05-31)The assemblage of Pleistocene megafauna at Waco Mammoth National Monument (WMNM) and the terrestrial Cretaceous-Paleogene (K-Pg) boundary at Big Bend National Park are just two examples that demonstrate the peril effects ... -
Targeting cancer through inhibition of cathepsin B by non-peptidic small molecule thiosemicarbazones and disruption of pre-existing vasculature by colchicine-like benzosuberene analogues.
(, 2014-01-28)Cancer is a leading cause of death in men and women under in the United States and is characterized by uncontrolled cellular proliferation and migration (metastasis) which can impinge on surrounding organs, modify ordinary ... -
Targeting Hypoxia with Small-Molecule Anticancer Agents
(2016-08-10)A vascular network delivers nutrients and oxygen to solid tumors, therefore selectively targeting tumor vasculature with anticancer agents represents a potentially promising therapeutic strategy. Small-molecule anticancer ... -
Targeting Intergenerational Homelessness: Addressing Cognitive Deficits with Parent-Child Intervention Therapy
(2017-05-24)Homelessness is a prevalent problem in modern day society. It is perpetuated by conditions of poverty that contribute to cognitive deficits. These cognitive deficits further the chance of chronic homelessness by decreasing ... -
Targeting the immune microenvironment to treat breast cancer.
(, 2014-06-11)In tumor microenvironment, the crosstalk between infiltrating inflammatory cells and tumor cells creates a cytokine milieu which can promote both oncogenesis and tumor rejection. We have found an IL-13 dominant cytokine ... -
Targeting the tumor microenvironment through the design and synthesis of potent, small-molecule, anticancer agents.
(, 2012-08-08)Targeting the vascular network that supplies a tumor with oxygen and nutrients is a viable methodology for the treatment of cancer. With the discovery of the combretastatin extended family of compounds in the late 1970's ... -
Targeting Tumor Hypoxia with Potent Vascular Disrupting Agents
(2016-08-09)Current therapeutic methods highlight the use of vascular disrupting agents (VDAs) in anti-cancer therapy. Through a binding interaction with the colchicine binding site on beta-tubulin, VDAs function as inhibitors of ... -
Tastefully Written: Reflections on Fiction and the Feast
(2014-06-02)From Homer to Shakespeare to Dostoyevsky, authors of fiction have found meal scenes prove to be rich repositories of symbolism. In the introductory chapter of this thesis, I attempt to answer the question of why authors ... -
Tatian’s Diatessaron in Latin : a new edition and translation of Codex Fuldensis.
(, 2014-06-11)When Tatian composed his Diatessaron in the second half of the second century, his text would have predated nearly all extant copies of the Gospels today. But his gospel harmony has not survived intact, either in Greek or ... -
Taurine : a novel approach to reducing the reinforcing properties of ethanol in adolescents.
(2011-05-12)Adolescent ethanol use continues to be a societal problem with ethanol drinking beginning as early as 11 years old. Early initiation of drinking behavior is indicative of an increased risk for future substance abuse problems. ... -
Taurine depletion in adolescent mice and implications for ethanol withdrawal-induced anxiety.
(2007-12-03)Adolescents exhibit few negative neurobehavioral effects of ethanol withdrawal and have higher levels of taurine, an inhibitory amino acid, than adults. Given taurine’s neuroprotective role and abundance during adolescence, ... -
Teachers and professional reading: a study of reading experience and administrative support across traditional, Paideia, and PDS schools.
(2006-05-27)The present study explored the perceived level of support teachers experience while pursuing professional reading as part of professional development. In order to do so, a descriptive study was designed to investigate the ... -
Teachers leaving the profession: the influence of violent student behavior on teacher attrition in Pennsylvania's public schools.
(2006-05-27)This study was conducted to develop a descriptive profile of school administrators responsible for human resources management in Pennsylvania’s public school districts relative to their perception of violent student ... -
Teachers' reasons for including field trips in the curriculum.
(, 2014-06-11)This dissertation examined the reasons' elementary teachers included field trips in the curriculum, whether increasing cultural capital, as defined by Pierre Bourdieu (1973), was one of their primary reasons, what types ... -
Teaching Business Ethics: A Faculty Seminar Model
(2007-12-20)Who is responsible for the increasing incidence of ethical misconduct in businesses? The short answer: the ones who committed the ethical misconduct are responsible. As these incidents receive more and more coverage ...