Browsing by Author "Kebaara, Bessie W."
Now showing items 1-5 of 5
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Characterization of a nonsense-mediated mRNA decay (NMD) copper regulon.
Peccarelli, Megan C., 1988- (2015-07-17)The nonsense-mediated mRNA decay (NMD) pathway was originally identified as a pathway that degrades mRNAs harboring premature termination codons. NMD is now also recognized as a pathway that degrades natural mRNAs. In ... -
CTR2 and the nonsense-mediated mRNA decay pathway in Saccharomyces cerevisiae.
Wang, Xuya. (, 2012-11-29)The nonsense-mediated mRNA decay (NMD) pathway recognizes and degrades mRNA with premature termination codon and some natural mRNA as well. CTR2 is a natural mRNA degraded by NMD in Saccharomyces cerevisiae. The goals of ... -
The role of CTR3 in the copper tolerance of nmd mutants of Saccharomyces cerevisiae
Walton, Mitchell (2013-05-24)The nonsense-mediated mRNA decay (NMD) pathway is a mechanism by which eukaryotic cells degrade mRNAs with nonsense codons and some natural mRNAs. CTR3 mRNA is a natural mRNA degraded by the pathway and codes for a copper ... -
The role of MAC1 in copper tolerance of Saccharomyces cerevisiae nonsense-mediated mRNA decay mutants
O'Connell, Danielle (2013-12-09)The nonsense-mediated mRNA (NMD) pathway, present in most eukaryotic cells is a specialized pathway that leads to the recognition and rapid degradation of mRNAs with premature termination codons and some natural mRNAs. The ... -
Yeast As a Model Organism To Assay the Functional Relevance of nsSNPS in Mitochondrial Disorders
Okani, Chidinma (2013-12-20)This thesis explores two yeast experiments. The first experiment, which was performed during the summers of 2011 and 2012, involved developing several yeast strains (including yeast strains with human wild-type orfeomes ...