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Copper ionophores induce autophagy in melanoma cells.
Malignant melanoma is a particularly aggressive form of skin cancer, for which the only current treatment option is excision. As melanoma is an inherently antiapoptotic model of cancer, other avenues of cell death were ...
Purification, characterization, and kinetic analysis of various metallo-β-lactamases and discovery of novel inhibitors of these enzymes.
Pathogenic bacteria are rapidly becoming antibiotic resistant, at a rate much faster than the production and FDA approval of new antibiotics that can combat these extreme resistant infections. One way to overcome antibiotic ...
Modifications of the small molecule maltol and photoactivity when coordinated to transition metals.
The family of hetero-substituted maltol chelators, thiomaltol (Htma), dithiomaltol (Httma), and 3-hydroxypyridine-4-thione (Hopto) have been used to generate complexes with Ru(II), Pt(II), Ti(IV), and P(III) that exhibit ...