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Identification of germline and somatic cell specific genes essential for ovulation in Caenorhabditis elegans.
The process of ovulation is an integral part of sexual reproduction in Caenorhabditis elegans. Various genes and signaling pathways are responsible for the successful process of ovulation to occur. Identification of these ...
Investigation of the role of ipp-5 and lfe-2 in the IP3 signaling pathway in Caenorhabditis elegans ovulation.
C. elegans provides a useful system with which to study signaling pathways, giving information that can be applied to many organisms. The use of RNA interference can be used to study the genes involved in many different ...
A novel computational method for predicting tissue-specific disease-associated signaling pathways in human utilizing Caenorhabditis elegans reference data.
Signal transduction is a hot topic as molecular biology grows because it directly relates to cellular processes, supporting function of the organism as a whole. A dysfunctional signal transduction will cause uncoordinated ...
The integrin interacts with cki-1/p27kip1, a tumor suppressor gene, of the nematode Caenorhabditis elegans.
Integrin is a heterodimeric cell surface receptor for extracellular matrix (ECM) and plays essential roles in regulating cell behaviors such as cell migration, adhesion, growth and death. The cell-ECM interaction is ...
Genetic screening for suppressor mutation in Caenorhabditis elegans odr-3 mutants
A suppressor mutation is a mutation that negates the effects of a different, separate mutation, facilitating a return to the wild-type phenotype. In this experiment, a suppressor mutation screen of a mutation of the odr-3 ...
Isolation of the him-4 suppressor mutation which rescues the vitality of C. elegans
The nematode Caenorhabditis contains hemicentin, which is a protein that aids in gonad development, as well as tissue formation. The him-4 gene, associated with the production of hemicentin, was used to observe the effects ...