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Bayesian and maximum likelihood methods for some two-segment generalized linear models.
The change-point (CP) problem, wherein parameters of a model change abruptly at an unknown covariate value, is common in many fields, such as process control, epidemiology, and ecology. CP problems using two-segment ...
Bayesian approaches to problems in drug safety and adaptive clinical trial designs.
The efficacy, safety, and cost of pharmaceutical products are critical issues in society today. Motivated both financially and ethically by these concerns, the pharmaceutical industry has continually worked to develop ...
Logistic regression with covariate measurement error in an adaptive design : a Bayesian approach.
Adaptive designs are increasingly popular in clinical trials. This is because such designs have the potential to decrease patient exposure to treatments that are less efficacious or unsafe. The Bayesian approach to ...