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Impact of neuroinflammatory and mTOR signaling inhibition following flurothyl seizures on the acute development of autistic-like behavior in C57BL/6 mice.
(2020-03-13)
Epilepsy is a common neurological disorder, with individuals having an increased susceptibility of seizures in the first few years of life. Children with epilepsy are at risk of developing a multitude of cognitive and ...
Peptidoglycome of gram-positive bacteria.
(2021-10-08)
Our modern healthcare system faces imminent threats from multidrug-resistant pathogens due to their unprecedented increase in the frequency of infections in clinical environment compounded by the lack of novel antibiotic ...
MISTR : a conserved MItochondrial STress Response network revealed by signatures of evolutionary conflict.
(2021-04-01)
As pathogens manipulate host-encoded master regulators, we hypothesized that molecular scars of host-pathogen conflicts-such as signatures of rapid evolution and viral mimics-could lead to the discovery of novel cellular ...
Plasmacytoid dendritic cell TLR7/9 response modulation through EGA and α-CD138 antibody.
(2021-05-28)
Plasmacytoid dendritic cells (pDC) have the unique ability to produce an inordinate amount of type 1 interferon (IFN) and other cytokines in response to stimulation with pathogenic and self-nucleic acids mainly through the ...