Search
Now showing items 1-3 of 3
Humanized mice to test vaccination against influenza virus via dendritic cells.
(2008-06-11)
Critical to the development of human vaccines is the availability of in vivo models of the human immune system that permit testing of vaccine efficacy. Here,we used NOD-SCID-β²m-/- immunodeficient mice which, when engrafted ...
Respiratory Syncytial Virus triggers immune tolerance through induction of tolerogenic dendritic cells and expansion of regulatory T cells.
(2010-06-23)
Dendritic cells have the ability to control the balance between immunity and tolerance. Upon viral exposure, Dendritic Cells (DCs) steadily detect pathogens and exert their antigen presentation function to induce adaptive ...
Gene expression profiling to understand the alterations in the monocyte compartment of pediatric systemic lupus erythematosus.
(2008-06-11)
Blood monocytes from SLE patients display DC function, as they are able to induce the proliferation of allogeneic T cells. Furthermore, sera from SLE patients induce healthy monocytes to differentiate into DCs. This ...