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    Effects of eight weeks of curcumin and Boswellia serrata supplementation on plasma markers of inflammation and antioxidant activity in chronic kidney disease patients.

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    Access changed 3/18/13.
    Date
    2010-10-08
    Author
    Moreillon, Jennifer Josephine.
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    Abstract
    The purpose of this study was to examine the effects of 8 weeks of curcumin and Bowellia serrata supplementation on changes in systemic inflammation and antioxidant activity in chronic kidney disease (CKD) patients. Sixteen CKD patients (56.0 ± 16.0 years, 171.4 ± 11.9 cm, 99.3 ± 20.2 kg) were randomized in a double blind fashion to ingest a daily supplement composed of 1340 mg of curcumin and Boswellia serrata (824 mg purified turmeric extract, 95% curcuminoids and 516 mg Boswellia serrata extract, 10% 3-acetyl-11-keto-beta-Boswellic acid) or 1340 mg of a roasted rice powder placebo. Patients provided fasting blood samples pre- and post-supplementation in order to assess changes in systemic inflammation and antioxidant activity. A 2 x 2 repeated measures MANCOVA with a probability level of 0.05 was used for the statistical analysis. No significant changes (p > 0.05) were observed for the indicators of inflammation, represented by plasma interleukin-6 and plasma tumor necrosis factor-alpha, as well as the indicator of antioxidant activity represented by plasma glutathione peroxidase. It appears that 8 weeks of curcumin and Boswellia serrata supplementation does not affect inflammation levels and antioxidant activity in CKD patients. More research is needed to determine the impact that curcumin and Boswellia serrata supplementation have on changes in inflammation and antioxidant activity in diseased populations.
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    http://hdl.handle.net/2104/8045
    Department
    Health, Human Performance and Recreation.
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    • Theses/Dissertations - Health, Human Performance and Recreation

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    Copyright © Baylor® University All rights reserved. Legal Disclosures.
    Baylor University Waco, Texas 76798 1-800-BAYLOR-U
    Baylor University Libraries | One Bear Place #97148 | Waco, TX 76798-7148 | 254.710.2112 | Contact: libraryquestions@baylor.edu
    If you find any errors in content, please contact librarywebmaster@baylor.edu
    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    TDL
    Theme by 
    Atmire NV