The cathepsin family of cysteine proteases is overexpressed in a variety of cancer cell lines. Cathepsin L, one such protease, is secreted into the extracellular space and plays a critical role in degrading the extracellular ...

Current therapeutic methods highlight the use of vascular disrupting agents (VDAs) in anti-cancer therapy. Through a binding interaction with the colchicine binding site on beta-tubulin, VDAs function as inhibitors of ...

In search of a more narrative-embedded approach to communication between players of video games, this paper provides the details of a study in which players are tasked with learning about other players merely through ...

In 2009, the federal government passed the American Recovery and Reinvestment Act as a stimulus bill. This bill included the Health Information Technology for Economic and Clinical Health (HITECH) Act, which provided ...

“The right to choose” has become one of the most contested phrases in discussions about education reform. Educators, advocates, elected officials, and parents are found on both sides of the debate. In today’s society, ...

The years between 229 BC and 146 BC saw a massive transformation of the relationship between Rome and her Greek neighbors. From antiquarian curiosity concerning Roman origins to hopeful approval and bitter opposition, the ...

When Mad Men first aired in the summer of 2007, it was more than just a television series with the uncanny ability to tap into the subconscious minds of its viewers, causing them to reminisce about a bygone era they may ...

Vascular disrupting agents (VDAs), a subclass of vascular targeting agents (VTAs), represent an emerging therapeutic strategy for targeting tumor vasculature to impart irreversible vessel damage leading to tumor necrosis. ...