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NS-Pten knockout mice show sex-and-age specific differences in ultrasonic vocalizations.
One signaling cascade that plays a crucial role in the development of an autistic-like phenotype is the PI3K/Akt/mTOR pathway. Mouse models that illustrate this connection include Fmr1, Tsc1, and NS-Pten deficient mice. ...
Acute agomelatine administration does not attenuate deficits in vocalizations, inflammation, or excitation in kainic acid treated pups.
Seizures during early-development result in an increase in proinflammatory cytokine production and impact communication behavior in murine models. Our study investigated the efficacy of the anti-inflammatory pharmaceutical ...