The change-point (CP) problem, wherein parameters of a model change abruptly at an unknown covariate value, is common in many fields, such as process control, epidemiology, and ecology. CP problems using two-segment ...

The efficacy, safety, and cost of pharmaceutical products are critical issues in society today. Motivated both financially and ethically by these concerns, the pharmaceutical industry has continually worked to develop ...

Adaptive designs are increasingly popular in clinical trials. This is because such designs have the potential to decrease patient exposure to treatments that are less efficacious or unsafe. The Bayesian approach to ...