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Anti-tumor activity of an oncolytic adenoviral construct expressing a small interfering RNA transgene.
(Philadelphia, PA : American Association for Cancer Research., 2006-10-01)
Cancer is a leading cause of mortality in the world today. Mutation in the K-ras oncogene is common in most human cancers. K-ras oncogene expression was specifically downregulated by 58.7% by K-ras silencing siRNA, and ...