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    Using a bioinformatics approach to identify genes that have possible candidacy of association with retinitis pigmentosa: GeneWeaver

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    Date
    2016-08-10
    Author
    Lie, Natasha
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    Abstract
    Retinitis pigmentosa (RP) is a retinal degenerative disorder that affects about 1 in 3,000 people. The disease is genetic in cause, and currently there is no cure. The genetic cause of the disease may be contributed to one of several different genes, underscoring the complex genetic underpinnings of this disease. The information required to determine which genes are potentially causative for RP may exist, but it is difficult to determine which genes are most suitable for study because of the immense wealth and breadth of available information. In other words, large-scale heterogeneous species-specific data often obfuscates the true causative genetic background of RP. In this study we describe a method of identifying genes that may contribute to RP using the bioinformatics techniques of graph theory and database utilization. We report a potential ranked list of genes in which disruptions are likely causative of RP.
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    http://hdl.handle.net/2104/9733
    Department
    Biochemistry.
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    Copyright © Baylor® University All rights reserved. Legal Disclosures.
    Baylor University Waco, Texas 76798 1-800-BAYLOR-U
    Baylor University Libraries | One Bear Place #97148 | Waco, TX 76798-7148 | 254.710.2112 | Contact: libraryquestions@baylor.edu
    If you find any errors in content, please contact librarywebmaster@baylor.edu
    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    TDL
    Theme by 
    Atmire NV