The Gut Microbiome & its Value in Autoimmune Diseases

Date

2021

Authors

Glass, Paige

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Worldwide access

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Abstract

The crucial effect of the gut microbiome in human function is not yet fully understood, but it is highly significant. The gut microbiome functions in nutrient metabolism, immune modulation, drug metabolism, intestinal barrier regulation, and defense against pathogens. Although its complete function in autoimmune diseases has not fully been elucidated, many studies have linked the gut microbiome to specific autoimmune diseases such as inflammatory bowel disease, type 1 diabetes, systemic lupus erythematosus, and rheumatoid arthritis. In this review, the function of each of the key microbial players is reviewed in order to allow for a greater understanding of how the gut microbiome contributes to autoimmune diseases. The microbiome shows potential as a diagnostic or therapeutic target in the treatment of autoimmune diseases through probiotics, diet, and fecal microbiota transplantation.

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