Preliminary investigation on optical cavity-based biosensor using double-sided tape.

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dc.contributor.advisorKim, Seunghyun.
dc.creatorSmith, Savanah, 2000-
dc.date.accessioned2024-07-30T12:44:17Z
dc.date.available2024-07-30T12:44:17Z
dc.date.created2023-12
dc.date.issued2023-12
dc.date.submittedDecember 2023
dc.date.updated2024-07-30T12:44:19Z
dc.description.abstractEarly detection is the key to improving survival rates of diseases like cancer. Biosensors and microfluidics can aid in making detection more affordable and accessible. Our team has developed a foundational optical cavity-based biosensor capable of biomarker detection using low-cost fabrication methods, components, and a differential detection method. This biosensor laid the foundation for the creation of a double-sided tape-based biosensor to make fabrication three times faster and 96% cheaper. Double-sided tape defines and bonds the microfluidic channel to maintain a controlled fluid flow without leaking. It can also be used to actively control the cavity width using pulse width modulation (PWM)-based actuation. Cavity width adjustment was demonstrated through beam profile movement (maximum 1.44 mm), optical resonance, and by reducing the time required to achieve the optimal cavity width region (2.6-minute average). Overall, the simulations and data show this cavity structure with double-sided tape is worth further optimization and testing.
dc.format.mimetypeapplication/pdf
dc.identifier.uri
dc.identifier.urihttps://hdl.handle.net/2104/12882
dc.language.isoEnglish
dc.rights.accessrightsNo access – contact librarywebmaster@baylor.edu
dc.titlePreliminary investigation on optical cavity-based biosensor using double-sided tape.
dc.typeThesis
dc.type.materialtext
local.embargo.lift2028-12-01
local.embargo.terms2028-12-01
thesis.degree.departmentBaylor University. Dept. of Electrical & Computer Engineering.
thesis.degree.grantorBaylor University
thesis.degree.nameM.S.E.C.E.
thesis.degree.programElectrical and Computer Engineering
thesis.degree.schoolBaylor University

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