Human Biological Variation and the Application of Personalized Medicine

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dc.contributor.advisorBaker, Lori
dc.contributor.authorHorton, Katherine
dc.contributor.departmentUniversity Scholars.en_US
dc.contributor.schoolsHonors College.en_US
dc.date.accessioned2013-05-24T20:34:27Z
dc.date.available2013-05-24T20:34:27Z
dc.date.copyright2013
dc.date.issued2013-05-24
dc.description.abstractMultidisciplinary advances have progressed the idea that medical therapy may be tailored to the genetics of an individual patient through personalized medicine. The concepts of race, ethnicity, and ancestry have been utilized as ways to describe human biological variation. Race is not a biological classification system but rather a cultural construct that changes through time. The study of DNA sequence, expression of RNA, proteins and their derivatives, and DNA methylation contribute to this growing field. Certain medications are prescribed in a manner tailored to human genetic variation. The anticoagulant warfarin is viewed as a case study of an application of personalized medicine. Further research into the connection between the efficacy of treatments and the ancestry of population groups is needed. This study has examined the connection between the anthropological understanding of human biological variation and the application of personalized medicine with warfarin as a specific example.en_US
dc.identifier.urihttp://hdl.handle.net/2104/8696
dc.language.isoen_USen_US
dc.rightsBaylor University projects are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. Contact libraryquestions@baylor.edu for inquiries about permission.en_US
dc.rights.accessrightsWorldwide accessen_US
dc.subjectHuman biological variation.en_US
dc.subjectPersonalized medicine.en_US
dc.titleHuman Biological Variation and the Application of Personalized Medicineen_US
dc.typeThesisen_US

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