The anabolic and anti-catabolic effects of long-chain omega-3 polyunsaturated fatty acid supplementation on functional muscular outcomes.


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Long-chain omega-3 polyunsaturated fatty acids (LC n-3 PUFAs) are associated with multiple benefits, primarily related to cognitive and cardiovascular health. Recently, LC n-3 PUFAs, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have received considerable attention from the athletic and military communities for their potential application to physical performance and recovery. While multiple lines of evidence have provided valuable insight into the plausible mechanisms, the influence of LC n-3 PUFAs on functional skeletal muscle outcomes remain elusive. As such, this dissertation will investigate the potential anabolic influence of LC n-3 PUFA supplementation on body composition and strength. Additionally, the differential effects of two bioactive LC n-3 PUFAs, EPA and DHA, on muscle recovery following exercise-induced muscle damage will be explored.