A Review of Hyperkalemic Periodic Paralysis and Proposal of A Symptom Mitigation Tool

Simple item page
dc.contributor.advisorKlausmeyer, Rizalia
dc.contributor.authorHughes, Aeleia
dc.contributor.departmentScience Research Fellows.en_US
dc.contributor.otherBaylor University.en_US
dc.contributor.otherSteve Kuenzli.en_US
dc.contributor.schoolsHonors College - Honors Programen_US
dc.contributor.schoolsHonors College - Honors Thesesen_US
dc.date.accessioned2020-09-02T13:19:57Z
dc.date.available2020-09-02T13:19:57Z
dc.date.copyright2020-07-23
dc.date.issued2020-09-02
dc.description.abstractHyperkalemic Periodic Paralysis (HyperPP) is a disease caused by a mutation of the SCN4A gene (Weber et al., 1993). This gene codes for the alpha-subunit of the voltage-gated Nav1.4 sodium channels found in skeletal muscle (George et al., 1993), which are essential to uniform muscle contraction (Weber et al., 1993). HyperPP manifests as episodes of flaccid muscle weakness, typically evident in the patient’s first decade of life. (Statland et al., 2018a). A possible trigger for HyperPP attacks is dietary potassium intake (V. Sansone et al., 2008). The aim of this paper is to discuss the onset mechanisms of HyperPP and current treatment pathways, and to propose an application capable of tracking the nutrient data of food items, including potassium content, to help patients mediate their symptoms. To determine the efficacy of this novel management tool, a study should be completed 12 months after it is released for public use.en_US
dc.identifier.urihttps://hdl.handle.net/2104/10971
dc.language.isoen_USen_US
dc.rightsBaylor University projects are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. Contact libraryquestions@baylor.edu for inquiries about permission.en_US
dc.rights.accessrightsWorldwide accessen_US
dc.subjectNutrition and Myotonia.en_US
dc.subjectHyperkalemic Periodic Paralysis.en_US
dc.subjectHyperkalemic Periodic Paralysis Symptom Management.en_US
dc.subjectHyperKPP.en_US
dc.subjectHyperPP.en_US
dc.subjectPeriodic Paralysis.en_US
dc.subjectScience Research Fellows.en_US
dc.subjectSCN4A gene mutation.en_US
dc.subjectSCN4A gene.en_US
dc.subjectPotassium Related Disorder.en_US
dc.subjectMyotonia.en_US
dc.subjectMuscle Constriction.en_US
dc.subjectNutrition and Periodic Paralysis.en_US
dc.titleA Review of Hyperkalemic Periodic Paralysis and Proposal of A Symptom Mitigation Toolen_US
dc.typeThesisen_US

Files

Original bundle

Now showing 1 - 3 of 3
Thumbnail Image
Name:
A Review of Hyperkalemic Periodic Paralysis and Proposal of A Symptom Mitigation Tool.pdf
Size:
1.6 MB
Format:
Adobe Portable Document Format
Description:
Download
No Thumbnail Available
Name:
Honor College Agreement.pdf
Size:
106.66 KB
Format:
Adobe Portable Document Format
Description:
Download
No Thumbnail Available
Name:
Honros College Agreement Signatures.pdf
Size:
64.22 KB
Format:
Adobe Portable Document Format
Description:
Download

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.87 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Theses - Honors College