• Login
    View Item 
    •   BEARdocs Home
    • Honors College
    • Theses - Honors College
    • View Item
    •   BEARdocs Home
    • Honors College
    • Theses - Honors College
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Potential Inhibitors of Bascillus anthracis’ Metallo- β-Lactamase by Hydroxamate Functional Groups and G-Quadruplex Aptamers

    Thumbnail
    View/Open
    Thesis (2.412Mb)
    Permissions Form (2.597Mb)
    Access rights
    Worldwide access.
    Access changed 8/25/15.
    Date
    2013-05-24
    Author
    Hermann, Megan
    Metadata
    Show full item record
    Abstract
    Antibiotic resistance is a growing problem among many strains of bacteria, especially within the populations that most commonly infect hospital patients. A variety of molecules have been found that are capable of inhibiting the enzymes responsible for conveying resistance in a number of bacterial strains, yet inhibition among certain strains of bacteria remains elusive. This study focuses on the inhibition of the metallo-β- lactamase enzyme found in Bascillus anthracis by novel hydroxamic acid-containing molecules and G-quadruplex-based DNA aptamers. These molecules proved to be potent inhibiting molecules and therefore present a promising avenue for further research to combat antibiotic resistance in bacteria.
    URI
    http://hdl.handle.net/2104/8660
    Department
    Biochemistry.
    Collections
    • Theses - Honors College
    

    Copyright © Baylor® University All rights reserved. Legal Disclosures.
    Baylor University Waco, Texas 76798 1-800-BAYLOR-U
    Baylor University Libraries | One Bear Place #97148 | Waco, TX 76798-7148 | 254.710.2112 | Contact: libraryquestions@baylor.edu
    If you find any errors in content, please contact librarywebmaster@baylor.edu
    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    TDL
    Theme by 
    Atmire NV
     

     

    Browse

    All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    Login

    Statistics

    View Usage Statistics

    Copyright © Baylor® University All rights reserved. Legal Disclosures.
    Baylor University Waco, Texas 76798 1-800-BAYLOR-U
    Baylor University Libraries | One Bear Place #97148 | Waco, TX 76798-7148 | 254.710.2112 | Contact: libraryquestions@baylor.edu
    If you find any errors in content, please contact librarywebmaster@baylor.edu
    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    TDL
    Theme by 
    Atmire NV