Improving Transplant Efficacy

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dc.contributor.advisorKane, Robert R.
dc.contributor.authorMurphy, Kayla
dc.contributor.departmentBiology.en_US
dc.contributor.schoolsHonors College.en_US
dc.date.accessioned2018-05-21T15:47:26Z
dc.date.available2018-05-21T15:47:26Z
dc.date.copyright2018
dc.date.issued2018-05-21
dc.description.abstractThe development of tissue and organ transplantation has been an important achievement in medicine. Extensive research into medications and preservation techniques has improved the success of transplants. However, ongoing research continues to find new ways to improve transplant efficacy and durability. Our area of transplant research involves the bioconjugation of immunosuppressant medications onto the surface of pancreas islet cells prior to transplantation. This thesis will introduce current advances into organ transplantation as well as significant challenges that remain. Chapter 2 will describe our research aimed at demonstrating the use of a novel anti-inflammatory medication in islet cell transplantation. Chapter 3 will present our investigations of chemical linkers as model studies to be extrapolated onto other tissue and organ types. Our research ultimately aims to create a more protective and safe biological environment for transplanted tissues.en_US
dc.identifier.urihttp://hdl.handle.net/2104/10234
dc.language.isoen_USen_US
dc.rightsBaylor University projects are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. Contact libraryquestions@baylor.edu for inquiries about permission.en_US
dc.rights.accessrightsWorldwide access.en_US
dc.rights.accessrightsAccess changed 7/31/20.
dc.subjectTransplantation.en_US
dc.subjectBioconjugation.en_US
dc.subjectImmunology.en_US
dc.subjectLinker Chemistry.en_US
dc.titleImproving Transplant Efficacyen_US
dc.typeThesisen_US

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