A beta regression approach to nonparametric longitudinal data classification in clinical trials.

Hernandez, Roberto Sergio, 1995-

A beta regression approach to nonparametric longitudinal data classification in clinical trials.

dc.contributor.advisor	Tubbs, Jack Dale.
dc.creator	Hernandez, Roberto Sergio, 1995-
dc.creator.orcid	0000-0003-3143-682X
dc.date.accessioned	2022-06-03T13:18:30Z
dc.date.available	2022-06-03T13:18:30Z
dc.date.created	2022-05
dc.date.issued	2022-04-07
dc.date.submitted	May 2022
dc.date.updated	2022-06-03T13:18:31Z
dc.description.abstract	Classification is an important topic in statistical analysis. For example, in applications involving clinical trials, an often seen objective is to determine whether or not novel medicines and treatments differ from existing standards of care. There are numerous methods and approaches in the literature for this problem when the endpoint of interest is normally distributed or can be approximated by an asymptotic Normal distribution, yet, the approaches when using a non-normally distributed endpoint are limited. This is especially true when these endpoints are correlated across time. In this dissertation, we investigated several techniques for use with longitudinal, repeated measures data where there is a special interest in adapting some recent results found in the literature on Beta regression. The proposed methods provided a nonparametric, with regard to the design endpoint, model that can be used in the repeated measures problem.
dc.format.mimetype	application/pdf
dc.identifier.uri	https://hdl.handle.net/2104/11947
dc.language.iso	en
dc.rights.accessrights	No access – contact librarywebmaster@baylor.edu
dc.subject	Longitudinal. Beta regression. Nonparametric placement values. ROC curve. Classification.
dc.title	A beta regression approach to nonparametric longitudinal data classification in clinical trials.
dc.type	Thesis
dc.type.material	text
local.embargo.lift	2027-05-01
local.embargo.terms	2027-05-01
thesis.degree.department	Baylor University. Dept. of Statistical Science.
thesis.degree.grantor	Baylor University
thesis.degree.level	Doctoral
thesis.degree.name	Ph.D.